| Summary | Opening Weekend Revenue | Opening Weekend Theaters | Release Date |
|---|---|---|---|
| Barbie | $162,022,044 | 4,243 | 2023-07-21 |
| Beetlejuice Beetlejuice | $111,003,345 | 4,575 | 2024-09-06 |
| The Hangover Part II | $85,946,294 | 3,615 | 2011-05-26 |
| The Simpsons Movie | $74,036,787 | 3,922 | 2007-07-27 |
| Austin Powers in Goldmember | $73,071,188 | 3,613 | 2002-07-25 |
| Pitch Perfect 2 | $69,216,890 | 3,473 | 2015-05-15 |
| Bruce Almighty | $67,953,330 | 3,483 | 2003-05-23 |
| Kung Fu Panda 4 | $57,989,905 | 4,035 | 2024-03-08 |
| 22 Jump Street | $57,071,445 | 3,306 | 2014-06-13 |
| Sex and the City | $56,848,056 | 3,285 | 2008-05-30 |
| Austin Powers: The Spy Who Shagged Me | $54,917,604 | 3,312 | 1999-06-10 |
| Ted | $54,415,205 | 3,239 | 2012-06-29 |
| Pokémon: Detective Pikachu | $54,365,242 | 4,202 | 2019-05-10 |
| Jackass 3D | $50,353,641 | 3,081 | 2010-10-15 |
| Neighbors | $49,033,915 | 3,279 | 2014-05-09 |
| Scary Movie 3 | $48,113,770 | 3,505 | 2003-10-24 |
| The Longest Yard | $47,606,480 | 3,634 | 2005-05-27 |
| Talladega Nights: The Ballad of Ricky Bobby | $47,042,215 | 3,803 | 2006-08-04 |
| Meet the Fockers | $46,120,980 | 3,518 | 2004-12-22 |
| Ghostbusters | $46,018,755 | 3,963 | 2016-07-15 |
| American Pie 2 | $45,117,985 | 3,063 | 2001-08-10 |
| Ghostbusters: Frozen Empire | $45,004,673 | 4,345 | 2024-03-22 |
| The Hangover | $44,979,319 | 3,269 | 2009-06-05 |
| Ghostbusters: Afterlife | $44,008,406 | 4,315 | 2021-11-19 |
| Nutty Professor II: The Klumps | $42,518,830 | 3,242 | 2000-07-28 |
| Scary Movie | $42,346,669 | 2,912 | 2000-07-07 |
| Anger Management | $42,220,847 | 3,551 | 2003-04-11 |
| The Hangover 3 | $41,671,198 | 3,555 | 2013-05-23 |
| Ocean’s 8 | $41,607,378 | 4,145 | 2018-06-08 |
| Big Daddy | $41,536,370 | 3,027 | 1999-06-25 |
| Ride Along | $41,516,170 | 2,663 | 2014-01-17 |
| Grown Ups 2 | $41,508,572 | 3,491 | 2013-07-12 |
| Madea Goes To Jail | $41,030,947 | 2,032 | 2009-02-20 |
| Grown Ups | $40,506,564 | 3,534 | 2010-06-25 |
| Scary Movie 4 | $40,222,875 | 3,602 | 2006-04-14 |
| Click | $40,011,365 | 3,749 | 2006-06-23 |
| Wild Hogs | $39,699,023 | 3,287 | 2007-03-02 |
| The Waterboy | $39,414,071 | 2,664 | 1998-11-06 |
| Magic Mike | $39,127,170 | 2,930 | 2012-06-29 |
| The Heat | $39,115,043 | 3,181 | 2013-06-28 |
| Daddy’s Home | $38,740,203 | 3,271 | 2015-12-25 |
| Get Smart | $38,683,480 | 3,911 | 2008-06-20 |
| You Don’t Mess With the Zohan | $38,531,374 | 3,462 | 2008-06-06 |
| Dr. Seuss’ The Cat in the Hat | $38,329,160 | 3,464 | 2003-11-21 |
| Ace Ventura: When Nature Calls | $37,804,076 | 2,652 | 1995-11-10 |
| The Flintstones | $37,182,745 | 2,498 | 1994-05-27 |
| Mr. Deeds | $37,162,787 | 3,231 | 2002-06-28 |
| Marley & Me | $36,357,586 | 3,480 | 2008-12-25 |
| 21 Jump Street | $36,302,612 | 3,121 | 2012-03-16 |
| Dumb and Dumber To | $36,111,775 | 3,154 | 2014-11-14 |
| The Other Guys | $35,543,162 | 3,651 | 2010-08-06 |
| Central Intelligence | $35,535,250 | 3,508 | 2016-06-17 |
| Ride Along 2 | $35,243,095 | 3,175 | 2016-01-15 |
| Identity Thief | $34,551,025 | 3,141 | 2013-02-08 |
| Sausage Party | $34,263,534 | 3,103 | 2016-08-12 |
| I Now Pronounce You Chuck and Larry | $34,233,750 | 3,495 | 2007-07-20 |
| Norbit | $34,195,434 | 3,136 | 2007-02-09 |
| Wedding Crashers | $33,900,720 | 2,925 | 2005-07-15 |
| Get Hard | $33,803,253 | 3,175 | 2015-03-27 |
| IF | $33,715,801 | 4,041 | 2024-05-17 |
| Ted 2 | $33,507,870 | 3,442 | 2015-06-26 |
| American Wedding | $33,369,440 | 3,172 | 2003-08-01 |
| Superbad | $33,052,411 | 2,948 | 2007-08-17 |
| Blades of Glory | $33,014,202 | 3,372 | 2007-03-30 |
| Due Date | $32,689,406 | 3,355 | 2010-11-05 |
| Jackass Presents: Bad Grandpa | $32,055,177 | 3,336 | 2013-10-25 |
| Paul Blart: Mall Cop | $31,832,636 | 3,144 | 2009-01-16 |
| Bad Teacher | $31,603,106 | 3,049 | 2011-06-24 |
| Liar Liar | $31,423,025 | 2,845 | 1997-03-21 |
| Girls Trip | $31,201,920 | 2,591 | 2017-07-21 |
| Evan Almighty | $31,192,615 | 3,604 | 2007-06-22 |
| Home Alone 2: Lost in New York | $31,126,882 | 2,222 | 1992-11-20 |
| Elf | $31,113,501 | 3,337 | 2003-11-07 |
| Bringing Down the House | $31,101,026 | 2,801 | 2003-03-07 |
| Four Christmases | $31,069,826 | 3,310 | 2008-11-26 |
| Space Jam: A New Legacy | $31,053,362 | 3,965 | 2021-07-16 |
| Sex and the City 2 | $31,001,870 | 3,445 | 2010-05-27 |
| Step Brothers | $30,940,732 | 3,094 | 2008-07-25 |
| Little Fockers | $30,833,665 | 3,536 | 2010-12-22 |
| The Dukes of Hazzard | $30,675,314 | 3,785 | 2005-08-05 |
| Brüno | $30,619,130 | 2,756 | 2009-07-10 |
| The Pacifier | $30,552,694 | 3,131 | 2005-03-04 |
| The Best Man Holiday | $30,107,555 | 2,024 | 2013-11-15 |
| Dodgeball: A True Underdog Story | $30,070,196 | 2,694 | 2004-06-18 |
| Madea's Family Reunion | $30,030,661 | 2,194 | 2006-02-24 |
| Daddy’s Home 2 | $29,651,193 | 3,575 | 2017-11-10 |
| Ghostbusters II | $29,472,894 | 2,410 | 1989-06-16 |
| Spy! | $29,085,719 | 3,711 | 2015-06-05 |
| Doctor Dolittle | $29,014,324 | 2,777 | 1998-06-26 |
| Meet the Parents | $28,623,300 | 2,614 | 2000-10-06 |
| Freakier Friday | $28,583,167 | 3,975 | 2025-08-08 |
| Tyler Perry’s Boo! A Madea Halloween | $28,501,448 | 2,260 | 2016-10-21 |
| Anchorman: The Legend of Ron Burgundy | $28,416,365 | 3,091 | 2004-07-09 |
| Nacho Libre | $28,309,599 | 3,070 | 2006-06-16 |
| Horrible Bosses | $28,302,165 | 3,040 | 2011-07-08 |
| Starsky & Hutch | $28,103,367 | 3,185 | 2004-03-05 |
| Big Momma's House 2 | $27,736,056 | 3,261 | 2006-01-27 |
| Daddy Day Care | $27,623,580 | 3,370 | 2003-05-09 |
| Cheaper by the Dozen | $27,557,647 | 3,298 | 2003-12-25 |
| The Devil Wears Prada | $27,537,244 | 2,847 | 2006-06-30 |